Published in Blood Weekly, June 28th, 2001
"Much toxicological research continues to be done using genetically undefined 'outbred' stocks of mice and rats, although the case for using isogenic strains has been made repeatedly in the literature over a period of more than two decades," wrote M.F.W. Festing and colleagues at the University of Leicester.
Festing and coworkers showed that toxicology tests using purebred mice can reveal more potential hazards of a potent drug than can testing with multiple strains...
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