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Epstein-Barr Virus

PCR Measurements Can Determine Treatment After Stem Cell Grafts

Published in Blood Weekly, September 6th, 2001

by Michael Greer, senior medical writer - Real-time measurement of Epstein-Barr virus (EBV) levels can help health care providers treat patients who develop EBV-related malignancies after stem cell transplantation, researchers in the Netherlands say.

"Epstein-Barr virus lymphoproliferative disease (EBV-LPD) following allogeneic stem cell transplantation (allo-SCT) has a poor prognosis," according to J.W.J. van Esser and colleagues at the University of Rotterdam Hospital.

However, the use of quantitative, real-time polymerase chain reaction (PCR) analysis to keep track of EPV loads allows doctors to rapidly determine the effectiveness of treatment...

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