Stem Cell Transplantation

Nitric Oxide Levels Can Predict Graft-Versus-Host Risk

Published in Blood Weekly, September 20th, 2001

by Michael Greer, senior medical writer - Plasma levels of nitric oxide shortly after stem cell transplantation are a prognostic factor for graft-versus-host disease, researchers in Hong Kong report.

"Nitric oxide (NO) has been implicated as one of the mediators of acute graft-versus-host disease (GVHD) but reports on its measurement during haemopoietic stem cell transplantation (HSCT) in human are scarce," according to Prof. Raymond Liang and colleagues at Queen Mary Hospital and the University of Hong Kong.

After taking and evaluating such measurements from stem cell recipients, Liang and coworkers found that elevated levels of NO byproducts were a...

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Source: Blood Weekly (2001-09-20)

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