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Stroke

Homocysteine gene implicated in spontaneous cervical artery tears

Published in Blood Weekly, April 4th, 2002

Italian researchers have found strong genetic evidence linking homocysteine to the type of strokes caused by tears in the artery wall, according to a report in the March 2002 issue of Stroke: Journal of the American Heart Association.

People in the study with elevated blood levels of homocysteine were significantly more represented in the group of patients with a form of stroke called spontaneous cervical artery dissection (sCAD) than stroke-free control subjects - 64% versus 13.9%. In addition, those with sCAD were also three times more likely to have two copies of the "T" version of the C677T MTHFR gene - 36% versus 11% - leading researchers to suspect...

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