Infectious Disease
Cytomegalovirus exposure ennervates dendritic cells
Published in Blood Weekly, May 2nd, 2002
"Dendritic cells (DCs) play a pivotal role in the generation of virus-specific cytotoxic T-cell responses, but some viruses can render DCs inefficient in stimulating T cells," according to Dr. Magdalena Moutaftsi and colleagues at the University of Wales in Cardiff and the Imperial College School of Medicine in London.
Exposure to human CMV (HCMV) prevents virus-specific DCs from signaling for cytotoxic activity, short circuiting the immune response to infection, Moutaftsi and coauthors...
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Source: Blood Weekly (2002-05-02)
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