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Stem Cell Research

Hematopoietic muscle cells originate in bone marrow

Published in Blood Weekly, June 6th, 2002

by Michael Greer, senior medical writer - A simple explanation may exist for mysterious hematopoietic stem cells found in muscle, researchers in the United States say.

"The nature of cells residing in muscle giving rise to hemopoietic colonies in vitro or hemopoietic reconstitution in vivo has been unclear," according to Dr. Surasit Issarachai and colleagues and colleagues at the University of Washington in Seattle.

However, these colonies probably result from the migration of bone marrow cells and not from a novel class of muscle-derived stem cells, Issarachai and coauthors said.

The researchers studied lethally irradiated mice...

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