Molecular Biology

Genetic discovery in fruit flies may open new avenues for understanding cancer growth in humans

Published in Blood Weekly, June 13th, 2002

Fred Hutchinson Cancer Research Center scientists report a finding in the common fruit fly that may open new paths for understanding some of the key genetic missteps that lead to cancer in humans. The discovery also could offer a better testing ground for anticancer drugs.

Susan Parkhurst, PhD, and Miriam Rosenberg, both of Fred Hutchinson's Basic Sciences Division, describe in the journal Cell how a gene called Sir2, long studied in yeast and worms, has a counterpart in fruit flies that plays a dynamic role in the genetic regulation of early development.

"Because of the important role of the Sir2 gene to basic life functioning, this gene has...

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Source: Blood Weekly (2002-06-13)

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