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Molecular Biology

Knockout blood protein drug signals possible new treatment for Alzheimer and diabetes

Published in Blood Weekly, June 13th, 2002

Scientists at the University College London (UCL) have developed a drug to treat a serious medical condition linked to Alzheimer disease and type 2 diabetes. The research, supported by the Medical Research Council (MRC) and reported in Nature, is the culmination of 25 years of basic and clinical research and the UCL scientists hope that it may be the key to the treatment of other serious diseases.

Crucially, Professor Mark Pepys and his team have managed for the first time to remove from the human body a naturally occurring blood protein - known as SAP - that is linked to development of the disease.

Amyloidosis - a disorder in which the...

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