Stem Cell Transplantation

Positive selection effective for autologous grafts from neuroblastoma patients

Published in Blood Weekly, June 13th, 2002

by Michael Greer, senior medical writer - Positive selection is a suitable purging technique for use with autologous stem cell grafts taken from children suffering from neuroblastoma, researchers say.

Dr. Rupert Handgretinger and colleagues at the Children's University Hospitals of Tuebingen, Koeln, and Frankfurt, and Olgahospital Stuttgart in Stuttgart, Germany, evaluated the safety and efficacy of positive CD34 selection in removing tumor cells from hematopoietic stem cell grafts.

This purging method is effective without degrading the graft's ability to engender hematopoietic reconstitution, Handgretinger and coauthors found.

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Source: Blood Weekly (2002-06-13)

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