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Hereditary Hemochromatosis

Nanogen expands genetic content patent portfolio

Published in Blood Weekly, July 18th, 2002

Nanogen, Inc., (NGEN) announced the issuance of U.S. Patent No. 6,355,425 (the '425 patent) entitled "Mutations Associated with Iron Disorders" relating to methods for the detection of certain mutations linked to hereditary hemochromatosis (HH).

HH is a genetically inherited disease that results in excess storage of iron, principally in the liver and bone joints. Nanogen has had an exclusive license to the '425 patent from Billups-Rothenberg, Inc., and Dr. Barry E. Rothenberg since 1998.

The '425 patent addresses identification and detection of mutations in the HFE gene, which is critical to diagnosing HH. Under this patent, Nanogen has exclusive...

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