Published in Blood Weekly, August 1st, 2002
"Hematopoietic stem cells (HSCs) are unique in their capacity to maintain blood formation following transplantation into immunocompromised hosts," explained Perpetua Pinto do O and colleagues at Umea University in Umea. "Expansion of HSCs in vitro is therefore important for many clinical applications but has met with limited success because the mechanisms regulating the self-renewal process are poorly defined."
Induced expression of the LIM-homeobox gene Lhx2 immortalizes multipotent stem...
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