Stem Cell Transplantation

Preradiotherapy growth factor treatment can improve engraftment

Published in Blood Weekly, September 5th, 2002

by Michael Greer, senior medical writer - Hematopoietic growth factor treatment could improve the outcome of autologous stem cell transplantation, researchers in the Netherlands report.

"Low-toxicity conditioning regimens prior to bone marrow transplantation (BMT) are widely explored," according to Estelle J. K. Noach and colleagues working at the University of Groningen.

By inducing differentiation in recipient stem cells, growth factor treatment prior to mild radiation-based conditioning enhanced long-term donor cell engraftment in mice, Noach and coauthors found.

Study animals received a combination of growth factors before...

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Source: Blood Weekly (2002-09-05)

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