Stem Cell Transplantation

Bone marrow grafts can trigger angiogenesis in ischemic limbs

Published in Blood Weekly, October 17th, 2002

by Michael Greer, senior medical writer - Bone marrow transplantation can promote the development of new blood vessels in ischemic limbs, researchers in Japan report.

"Preclinical studies have established that implantation of bone marrow-mononuclear cells, including endothelial progenitor cells, into ischaemic limbs increases collateral vessel formation," according to Eriko Tateishi-Yuyama and colleagues at Kansai Medical University in Osaka, the Kurume University School of Medicine in Kurume, and Jichi Medical School in Tochigi.

A pilot clinical study by Tateishi-Yuyama and coauthors showed that such treatment could be safe and effective.

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Source: Blood Weekly (2002-10-17)

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