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Stem Cell Transplantation

Expanded clonal T cell levels predict favorable response to photopheresis treatment

Published in Blood Weekly, November 7th, 2002

by Michael Greer, senior medical writer - Researchers in the United States have identified a positive prognostic indicator for patients undergoing photopheresis treatment for graft-versus-host disease after stem cell transplantation.

"Chronic graft-versus-host disease (cGvHD) is a multiorgan disorder with skin manifestations resembling scleroderma," explained Lars E. French and colleagues at the University of Pennsylvania in Philadelphia and Tufts New England Medical Center in Boston.

Amplified clonal T cell populations after stem cell transplantation predict a favorable outcome after photopheresis treatment for cGvHD, French and coauthors...

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