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Antithrombin Deficiency

Clinical safety and efficacy trial of rhATIII begins

Published in Blood Weekly, January 9th, 2003

GTC Biotherapeutics, Inc., (GTCB) announced the initiation of a safety and efficacy study of its recombinant human antithrombin III (rhATIII) for the treatment of patients with a hereditary deficiency (HD) of the antithrombin blood protein.

This trial will be conducted in those patients who are in high-risk situations for the development of thromboses. The first patient has received treatment in the study. This study is expected to be the final clinical trial before submission for European registration.

The trial is an open-label, single-arm study including at least 12 patients. This is a multinational study conducted primarily in Europe in...

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