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Biomaterials

Biological support sleeve improves collagen-based tissue engineered vascular constructs

Published in Blood Weekly, March 20th, 2003

A biological support sleeve improves the stamina of collagen-based tissue engineered vascular constructs.

"Various approaches to tissue engineering a small diameter blood vessel have historically relied upon extended culturing periods and/or synthetic materials to create mechanical properties suitable to withstand the hemodynamic stresses of the vasculature," according to a recent study from the United States.

J. D. Berglund and colleagues at the Georgia Institute of Technology assessed the utility of a "construct-sleeve hybrid (CSH) graft, which uses a biological support to provide temporary reinforcement while cell-mediated remodeling of the...

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