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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . April 3rd, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Multiple Sclerosis - Autologous stem cell transplantation can be beneficial

Stem Cell Transplantation - Donor pretreatment with IL-18 prevents acute GVHD

Epidemiology - Drug use and blood products transmit hepatitis C virus infections in Uzbekistan

HIV/AIDS Therapy - Different blood cell types have varying drug resistance rates

Orthopedics - Extended thromboprophylaxis recommended after hip or knee replacement

Stem Cell Research - Transplanted bone marrow generates new neurons in human brains

Acute Lymphoblastic Leukemia - Bone marrow grafts may be best option with matched unrelated donors

Acute Renal Failure - Selective inhibition of alternative pathway protects kidneys from ischemic ARF

Advanced Kidney Disease - Research: At-home dialysis therapy may be an effective option

Anemia - FDA warns of bacteria-tainted fake drug

Anticancer Therapeutics - Anthrapyridazone derivatives are active, even on multidrug resistant cells

Blood Substitute - Prehospital trauma trial with PolyHeme gets clearance

Bone Marrow - The alcaloid swainsonine has a significant stimulatory effect on bone marrow

Cancer Metastasis - Thrombin generation correlates with biomarkers in advanced prostate cancer

Cancer Predictors - Thromboembolism precedes cancer; should be considered risk marker

HIV/AIDS Gene Therapy - Cyclophilin A binding region blocks lentiviral vector simian cell transduction

HIV/AIDS Pathogenesis - Syndecan plays key role

HIV/AIDS Therapy - Cytokine profile changes linked to effective treatment

Hematology - Adeno-associated virus extends gene transfection in hemophilia models

Hematology - Strong static magnetic field had no effect on normal lymphocytes

Hematopoiesis - An autocrine-paracrine loop potentiates megakaryocytic maturity through Flt1

Hemodialysis - Off-pump coronary artery bypass grafting feasible for chronic dialysis patients

Hemophilia - NovoSeven is effective for surgery patient with previous history of inhibitors

Hemophilia - Osteotomy for hemophilic arthropathy of the knee especially aids young patients

Hemophilia - rFVIIa efficacious in treatment of major bleeding episodes

Hemorrhagic Shock - Navy to help fund and conduct clinical trial of Hemopure in trauma

Infectious Disease Diagnosis - Rapid immunoassays suitable for Clostridium difficile detection

Kidney Transplantation - Post-transplant monitoring by immune parameters may be preferable to drug level

Leukemia -  Lithospermum radix extract inhibits antiapoptosis kinase in tumor cells

Leukemia - Novel assay identifies T cells responsible for therapeutic, destructive stem cell graft activity

Medical Errors - Action taken by FDA to mandate bar codes on human drug products and blood

Non-Small Cell Lung Cancer - A vascular factor associates with plasma components in lung cancer patients

Pediatrics - The TT virus has been detected in children with acute respiratory disease

Pneumonia - Expression of Duffy antigen on alveolar septa is associated with infection

Stem Cell Research - Refined colony-forming unit-megakaryocyte assay suitable for toxicologic testing

Stem Cell Therapy - Teen first ever to get experimental stem cell heart treatment

Stem Cell Transplantation - CXCR4 cleavage may mediate progenitor cell mobilization

Stem Cell Transplantation - Fludarabine with cyclophosphamide lowers GVHD risk in mice

Stem Cell Transplantation - Low-dose donor lymphocyte infusions effective after haploidentical transplants

Stem Cell Transplantation - Nonmyeloablative transplantation may be gonadotoxic

Stem Cell Transplantation - Reduced-intensity conditioning widens transplant eligibility

Thromboembolism - Some chemotherapeutic agents alter regulation of thrombin on cell surfaces

Transfusion Medicine - Recent observations of aggregation in collected blood to be studied

Transplant Medicine - OPTN/UNOS review of transplant error continues

Urology - Genitourinary manifestations of hematologic diseases are becoming more common

Virology - Evolution of hepatitis C virus in blood donors differs from that of recipients

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