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Orthopedics

Extended thromboprophylaxis recommended after hip or knee replacement

Published in Blood Weekly, April 3rd, 2003

Doctors in private orthopedic practice recommend extended thromboprophylaxis (once daily for four weeks) after hip or knee replacement.

"Early discharge from the hospital after total joint arthroplasty has increased the need for extended outpatient thromboprophylaxis. Multiple controlled clinical trials and several meta-analyses of these data have examined various agents in different regimens. These data indicate that extended prophylaxis with a low-molecular-weight heparin after knee or hip arthroplasty significantly reduces the number of venous thromboembolic episodes with no increases in major bleeding," wrote R.J. Friedman and colleagues.

They...

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