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Bone Grafting

Adding a bone marrow clot to enriched bone matrix improves graft performance

Published in Blood Weekly, April 10th, 2003

Adding a bone marrow clot to enriched bone matrix improves graft performance.

"Bone marrow-derived cells including osteoblastic progenitors can be concentrated rapidly from bone marrow aspirates using the surface of selected implantable matrices for selective cell attachment. Concentration of cells in this way to produce an enriched cellular composite graft improves graft efficacy," researchers in the United States report.

"The current study was designed to test the hypothesis that the biologic milieu of a bone marrow clot will significantly improve the efficacy of such a graft. An established posterior spinal fusion model and cancellous bone...

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