Published in Blood Weekly, April 10th, 2003
A study from Poland "evaluated immunocytochemistry cellular localization and time-dependent expression of tumor necrosis factor (TNF-alpha) and its receptors p55 (TNF-R1) and p75 (TNF-R2) in human ischemic brains. We observed them in microglia, neurons, astrocytes, macrophages, and blood vessels. Since TNF-alpha expression was very intense and prolonged in microglia, it probably constitutes the main cellular source of the cytokine following cerebral ischemia in humans."
"Constitutive expression of TNF-alpha receptors was observed in neurons and blood vessels while in other...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.