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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . April 24th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Stem Cell Research - Bone marrow side population cells may aid liver regeneration

Stem Cell Research - Early-acting antiapoptotic cytokines prevent radiation damage

Amyotrophic Lateral Sclerosis - Stem cells contribute to tissue regeneration in mice

Aplastic Anemia - Patients show good response to combination therapy in NIH study

Leukemia Therapy - ST1571 pretreatment improves donor lymphocyte infusion efficacy

Umbilical Cord Blood - Sampling site affects blood acidity test results

Alcohol Consumption - An ethanol binge can promotes T cell apoptosis of up to 20%

Appointments - i-STAT appoints director of marketing

Autoimmune Disease - Genetically modified bone marrow could reverse some autoimmune disorders

Bartonella Quintana -  B. quintana persistence is linked to overproduction of IL-10

Biomaterials - Bone marrow stromal cells improve bone healing effects of titanium fiber

Blood Product - Human factor VIII product AAFACT safe for hemophilia A patients

Blood Shortage - Blizzard impacts community blood supply

Blood Testing - Umbilical cord blood screening can detect pure tetrasomy 20p

Cancer Therapy - CPT-11 effective against myelodysplastic syndromes with blast excess

Cancer Therapy - Etoposide-loaded red blood cells effective in mice.

Cytokine Receptor - Loss of TACI causes fatal lymphoproliferation and autoimmunity

Cytokines in PBMC - Monocytes produce increased Th1 cytokine IL-12 in normal human pregnancy

Environmental Toxins - Blood mercury levels low in most women of childbearing age and children

Fanconi Anemia - Telomere metabolism linked to severe aplastic anemia risk

HIV/AIDS Pathogenesis - DC-SIGN has cell-type dependent role in viral entry

Hemophilia - Desmopressin effective for home use in mild cases

Hypereosinophilic Syndrome - Study offers hope for patients with rare blood cancer

Infectious Disease - Ciprofloxacin alters CY pharmacokinetics, cytochrome P450 transcription

Kidney Disease - Alonzo Mourning visits Chicago to increase awareness of anemia

Laser Scanning Cytometry - LSC revealed that tyrosine phosphorylation is deranged by diet restriction

Leukemia Therapy - Alpha-tocopherol reduces cisplatin toxicity

Leukemia Therapy - HA-1- or HA-2-specific T cells can induce complete remission after relapse

Leukemia Therapy - Imatinib exacerbates idarubicin-induced hematopoietic toxicity

Leukemia Therapy - Interleukin-2 with GM-CSF effective in mice

Leukemia Therapy - Timed sequential therapy with ATRA effective in adult patients

Lung Cancer - Serum microparticles from monocytes, platelets may signal vascular complication

Lymphoma - Proliferation gene expression may have prognostic value

Lymphoma Therapy - Stem cell autografts effective against mantle cell lymphoma in remission

Memory T Cells - CD8+ central and effector subsets appear to have distinct origins

Minority Health - Increased iron stores are a challenge to African-Americans with hepatitis C

Multiple Myeloma - Thalidomide may delay progression of early-stage disease

Persistent Infection - Blood contains a low CD8 expressing T cell cytotoxic/effector subpopulation

Polymorphonuclear Neutrophil - PMNs express molecules required for antigen presentation and cell signaling

Sickle Cell Disease - Exhaled nitric oxide is decreased in sickle cell disease

Sickle Cell Disease - Major study: Hydroxyurea reduces mortality by 40%

Sickle Cell Disease - Researchers say deadly twist key to illness

Stem Cell Research - Cord blood stem cell market in Asia creating strong demand

Stem Cell Research - Different p38 MAPK levels have discrepant effects on erythroid progenitors

Stem Cell Research - Mixed lineage leukemia oncoprotein transforms multipotent hematopoietic progenitors

Stem Cell Research - Osteoblast progenitor cells found in umbilical cord blood

Stem Cell Research - Pluripotent stem cells derived from adult monocytes

Stem Cell Research - Stem cells could be used to treat diabetes

Stem Cell Research - TCDD exposure impaires long-term reconstitution activity

Stem Cell Transplantation - Early treatment needed against CNS aspergillosis

Stem Cell Transplantation - FTY720 reduces GvHD risk without affecting graft efficacy

Stem Cell Transplantation - Single large apheresis recommended for collection

Stem Cell Transplantation - T-cell effector gene transcripts predict acute GVHD

Stroke - Rat study: Treatment with blood cord cells holds promise

Transfusion Medicine - Catheter-free peripheral blood stem cell harvests feasible for small children

Transfusion Medicine - Major milestone reached with 100th hospital contract

Transfusion-Transmitted Virus - TT virus markers can be detected throughout the tissues of infected individuals

Tuberculosis Vaccine -  M. bovis BCG induces cord blood dendritic cell maturation

West Nile Virus - $2.47M of contract funding received from NIH for assay development

West Nile Virus - FDA accepts IND for Procleix assay

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