Stem Cell Research
Different p38 MAPK levels have discrepant effects on erythroid progenitors
Published in Blood Weekly, April 24th, 2003
"There have been conflicting reports regarding the role of p38 mitogen-activated protein kinase (MAPK) in the regulation of differentiation, proliferation and apoptosis in erythroid cell lines," according to a recent study from, UK.
To elucidate the effects of p38 MAPK, T. C. P. Somervaille and coauthors at Royal Free and University College Medical School "examined the functions of this kinase in primary human erythroid progenitors."
"Cells in steady-state culture showed low-level p38 MAPK activity," they found, "which decreased further within 1 hour...
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Source: Blood Weekly (2003-04-24)
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