Stem Cell Research

Pluripotent stem cells derived from adult monocytes

Published in Blood Weekly, April 24th, 2003

Highly plastic adult stem cells can be derived from peripheral blood.

Researchers in the United States "identified, cultured, characterized, and propagated adult pluripotent stem cells (PSC) from a subset of human peripheral blood monocytes."

"These cells, which in appearance resemble fibroblasts, expand in the presence of macrophage colony-stimulating factor and display monocytic and hematopoietic stem cell markers including CD14, CD34, and CD45," according to Y. Zhao and coauthors at Argonne National Laboratory.

"We have induced these cells to differentiate into mature macrophages by lipopolysaccharide, T lymphocytes by IL-2,...

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Source: Blood Weekly (2003-04-24)

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