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Aplastic Anemia

Patients show good response to combination therapy in NIH study

Published in Blood Weekly, April 24th, 2003

More than half (60%) of 122 patients with severe aplastic anemia enrolled in a long-term clinical trial treated with a combination of immunosuppressive agents - equine antithymocyte globulin (ATGAM) lymphocyte immune globulin antithymocyte globulin [equine] sterile solution and cyclosporine - demonstrated significantly increased blood cell counts as early as 3 months into treatment, according to a study conducted within the U.S. National Institutes of Health (NIH).

For patients who responded at 3 months, 86% were alive after 5 years. Overall survival of patients 7 years following combination therapy was 55%, according to the study, published in the Journal of the...

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