Chronic Renal Failure

Erythropoietin treated patients may develop a treatable autoimmune response

Published in Blood Weekly, May 1st, 2003

Renal failure patients with anemia given erythropoietin alpha who develop pure red blood cell aplasia can be treated with cyclosporine for resolution of autoimmune response.

According to a study from Singapore, "Human recombinant erythropoietin is the main treatment for anemia in renal patients. Recently, there have been case reports of pure red blood cell aplasia (PRCA) developing in renal patients administered erythropoietin, probably because of neutralizing antibodies detected in all these patients. All reports were from the West, and most patients were treated with erythropoietin-alpha.

"Cyclosporine is an immunosuppressive agent used to treat...

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Source: Blood Weekly (2003-05-01)

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