Endotoxin

Blood poisoning vaccine ready for human trials

Published in Blood Weekly, May 1st, 2003

A combined British and U.S. research team has developed the world's first vaccine against endotoxin, which is a key cause of blood poisoning and death after major surgery for cancer or heart disease.

The announcement was made at the Society for General Microbiology's Spring Meeting in Edinburgh.

"Most people make a rapid and successful recovery from major surgery," said Monty Mythen, professor of anesthesia and critical care at University College, London. "But we have discovered that people who take a long time to recover, or even die, often have low levels of natural defense against a dangerous byproduct of bacteria called endotoxin."

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Source: Blood Weekly (2003-05-01)

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