Published in Blood Weekly, May 15th, 2003
According to recent research published in the journal Biochemical Pharmacology, "Hematopoietic progenitor cells from children with Fanconi anemia of the C complementation group (FA-C) are excessively apoptotic and hypersensitive to various extracellular cues including Fas-ligand, tumor necrosis factor-of and double-stranded (ds) RNA. IFN-gamma is known to augment apoptotic responses of these factors.
"The priming effect of IFN-gamma is not fully explained. In view of the strong evidence that FA cells are intolerant of oxidative...
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