Immunology

Mannan-binding lectin doesn't correlate with vulnerability to hepatitis C virus

Published in Blood Weekly, May 15th, 2003

Mannan-binding lectin doesn't correlate with vulnerability with hepatitis C virus.

"Japanese patients with chronic hepatitis C infection unresponsive to treatment with interferon possessed genotypes disproportionately conferring low mannan-binding lectin (MBL) concentrations. Our aims were to confirm or refute this finding in European patients at the MBL protein level, and to investigate whether a low circulating concentration of MBL might influence susceptibility to, or disease progression from, hepatitis C viral infection," scientists in Scotland reported.

"Serum samples obtained from 180 hepatitis C patients and 566 blood donors were assayed for...

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Source: Blood Weekly (2003-05-15)

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