Hematology
Hematopoietic stem cells are successfully targeted with adenoviral transduction
Published in Blood Weekly, May 15th, 2003
According to recent research from the United States, "hematopoietic stem cells (HSC) are quiescent, self-renewing cells that can give rise to all blood cell lineages. HSC are an attractive target for gene therapy, due to their differentiation capacity and the number of diseases that result from abnormal HSC function. While human HSC have been shown to be transduced with adenoviral vectors, the adenoviral transduction of mouse HSC has not been extensively studied."
"We show here that a population of mouse bone marrow highly enriched for HSC (called side population,...
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Source: Blood Weekly (2003-05-15)
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