Acute Lymphoblastic Leukemia
Intensified GVHD prophylaxis enables haploidentical stem cell transplants
Published in Blood Weekly, June 5th, 2003
Researchers in Japan described their experience treating "a patient with refractory T-cell acute lymphoblastic leukemia who successfully underwent unmanipulated stem cell transplantation from an HLA 3-loci mismatched (haploidentical) sibling."
"In order to avoid severe graft-versus-host disease (GVHD), we used intensified GVHD prophylaxis consisting of tacrolimus, a short course of methotrexate, methylprednisolone, and mycophenolate mofetil," K. Ikegame and coauthors wrote in the journal Bone...
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Source: Blood Weekly (2003-06-05)
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