Stem Cell Research
Pumilio proteins expressed by murine hematopoietic cells
Published in Blood Weekly, June 5th, 2003
"Self-renewal is the common functional property of all types of stem cells and is thought to be regulated by unknown conserved intrinsic and extrinsic molecular mechanisms," researchers in the United States noted. "Recently, an evolutionarily conserved Pumilio family of RNA-binding proteins that regulate asymmetric cell division was found to be essential for stem cell maintenance and self-renewal in Drosophila and Caenorhabditis elegans."
"Based on conserved function in invertebrates and lower vertebrates it was recently proposed that an...
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Source: Blood Weekly (2003-06-05)
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