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Stem Cell Transplantation

Injury signals promote donor ocular cell incorporation

Published in Blood Weekly, June 12th, 2003

Injury signals promote incorporation of transplanted ocular stem cells.

"The incorporation of transplanted cells into the host retina is one of the prerequisites for successful cell replacement therapy to treat retinal degeneration," scientists in the United States noted.

"To test the hypothesis that injury promotes cell incorporation, stem cells/progenitors were isolated from the retina, ciliary epithelium or limbal epithelium and transplanted into the eyes of rats with retinal injury" in a study conducted by D.M. Chacko and coauthors at the University of Nebraska.

"Different stem cell/progenitor populations incorporated into...

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