Published in Blood Weekly, June 12th, 2003
In a recent study from the United States, ex vivo-expanded MSCs "were transduced with a green fluorescent protein (GFP) retroviral construct and subsequently infused into three adult baboons following lethal total body irradiation and hematopoietic support, or without any prior conditioning."
"To study the long-term fate of these MSCs, necropsies were performed between nine and 21 months following MSC infusion, and an average of 16 distinct tissues were recovered from each recipient and evaluated for the presence of the GFP transgene in purified genomic DNA by...
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