Myelodysplastic Syndromes
Mitochondrial DNA mutations play little role in development
Published in Blood Weekly, June 12th, 2003
Scientists in the United States "undertook to systematically analyze the entire mitochondrial genome by gene amplification and direct sequencing in 10 patients with myelodysplasia".
The "results were compared with eight concomitantly studied healthy volunteers as well as mtDNA sequences in a standard database," according to M.G. Shin and coauthors at the National Heart, Lung and Blood Institute in Bethesda, Maryland. "Nucleotide changes that were present in our healthy controls as well as those in published databases were counted as polymorphisms."
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Source: Blood Weekly (2003-06-12)
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