Stem Cell Transplantation

Molecular HLA typing prevents complications with unrelated grafts

Published in Blood Weekly, June 19th, 2003

by Michael Greer, senior medical writer - Researchers in Europe have found a way to prevent complications in children receiving hematopoietic stem cell transplants from unrelated donors (URD-HSCT).

S. Giebel and colleagues at the University of Pavia and IRCSS Policlinico San Matteo in Pavia, Italy and the Silesian Medical Academy in Katowice, Poland examined the utility of high-resolution molecular HLA typing of URD stem cells.

Children whose stem cell donors were chosen by the results of molecular typing had a low risk of graft rejection or graft-versus-host disease (GVHD), Giebel and coauthors reported.

They assessed the...

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Source: Blood Weekly (2003-06-19)

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