Published in Blood Weekly, June 26th, 2003
"Sonic hedgehog is involved in eye field separation along the proximodistal axis," researchers working at the University of Paris explained.
In their study, M. Perron and coauthors demonstrated that "Hh signalling continues to be important in defining aspects of the proximodistal axis as the optic vesicle and optic cup mature," showing that "two other Hedgehog proteins, Banded hedgehog and Cephalic hedgehog, related to the mouse Indian hedgehog and Desert hedgehog, respectively, are strongly expressed in the central retinal pigment epithelium but excluded from the peripheral...
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