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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . July 3rd, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Stem Cell Transplanation - Low molecular weight heparin safe for hepatic VOD prevention

Stem Cell Transplantation - NK-92 autograft purging effective

Stem Cell Research - New class of human stem cells discovered

Stem Cell Research - Prostaglandin E-2 induces osteoclast differentiation of hematopoietic bone marrow cells

Stem Cell Research - Wnt signaling involved in hematopoietic cell self-renewal

Umbilical Cord Blood - Novel myeloid-like NK cell progenitor identified

AIDS-related Lymphoma - HAART appears to have caused biological shift towards more treatable disease

Acute Lymphoblastic Leukemia - Unrelated stem cell grafts improve survival for children with high recurrence risk

Acute Myelogenous Leukemia - More cytokines are produced by circulating lymphoid and myeloid cells in AML

Acute Myeloid Leukemia - Gemtuzumab ozogamicin may be effective for pediatric patients

Adult Stem Cells - Alternatives to human embryonic stem cells promoted

Antibiotic Resistance -  Serratia species have multiple mechanisms, including unique beta-lactamases

Autologous Blood Transfusion - Leukocyte depletion prior to storage sometimes will not filter well

Bioengineering - "Immortalized" cells enable researchers to grow human arteries

Blood Products - Glycine-treated products can be stored briefly and used after opening

Blood Safety - FDA issues 510(k) clearance for new blood banking system

Blood Testing - Novel flow cytometry assay can measure lymphocyte levels in RBC-contaminated samples

Bone Marrow Transplantation - BMT can be successful in subjects with mental disorders

Bone Marrow Transplantation - Survival not substantively affected by depressed mood or other psychopathology

Brain & Spinal Cord Damage - IV infusions of human umbilical cord blood stem cells benefit rodents with ALS

Bullous Pemphigoid - Plasmapheresis was used to sucessfully lower the titers of autoantibodies

Cancer Therapy - EntreMed and Corvas scientists identify new cancer target

Colorectal Lymphoma - The first case of primary colorectal T-cell lymphoma is reported

Critical Care Medicine - Novel liquid occlusive effective for wound dressing

Diagnostics - Capillary electrophoresis immunoassay is comparable to chemiluminescence

Finance - Private placement funds will further develop stem cell technology

Financing - Blood safety company closes new financing

Genetic Disease - Griscelli syndrome without hemophagocytosis occurs with a new Rab27A mutation

Group B Streptococcus - Incidence of sepsis could be underestimated in newborns

Hematological Cancer - Dual cancers can coexist: Chronic lymphocytic leukemia and mantle cell lymphoma

Hematology - Patients with chronic hepatitis C and mixed cryoglobulinemia undergo apheresis

Hematology - Phase I data on suberoylanilide hydroxamic acid presented

Hematology - Thrombospondin-2 is required for megakaryocyte formation and function

Intravascular Coagulation - Tissue factor messenger RNA is higher in cancer and hypercoagulable diseases

Kidney Disease - New study shows patients at risk for kidney disease may benefit from new therapy

Kidney Transplant - Delayed graft function worsens with reduced pressure reperfusion

Kidney Transplant - Microchimerism can be avoided by perfusing out donor kidney lymphocytes

Kidney Transplantation - Analysis: Neoral improves graft survival in living-donor transplant patients

Leukemia - Breastfeeding does not protect children from acute lymphocytic leukemia

Liver Transplantation - Eosinophilia counts have limitations as liver graft rejection screening tools

Lymphoma - Epstein-Barr virus-associated T-cell lymphoma can develop after renal transplant

Multiple Myeloma - Initial clinical data reported from phase I/II trial of GVAX vaccine

Myasthenia Gravis - Some patients have autoreactive T cells to an acetylcholine receptor subunit

Neurology - Motor nerve cell findings may yield treatments for spinal cord injury, disease

Neutrophil Recruitment/Adhesion - Endothelial cell inflammatory response to endotoxin needs actin polymerization

Nosocomial Infection - Efforts to reduce viral hepatitis transmission by health workers fall short

Oroya Fever -  Bartonella bacilliformis IalB is expressed with low pH and temperature

Over-reactive Platelets - Study finds clopidogrel not effective in certain patients

Pretransplant Transfusion - Tolerization appears to happen after what would seem to be a normal Th1 response

Pulmonary Medicine - Stem cell antigen-1 reveals information about pulmonary vascular endothelium

Renal Transplantation - TT virus group 1 variants prevail among kidney transplant recipients

Sickle Cell Disease - NaPro's gene editing demonstrates gene alteration in human cells

Stem Cell Research - Complement anaphylatoxin C3a involved in homing to bone marrow

Stem Cell Research - Embryonic cells can differentiate into transplantable hepatocytes

Stem Cell Research - Hydrostatic pressure can enhance mesenchymal progenitor cell differentiation

Stem Cell Research - Neural stem cells take a step closer to the clinic

Stem Cell Research - Spermatogonial cell expansion possible

Stem Cell Research - Tyrosine kinase activity increased in leukemic mice

Stem Cell Transplantation - Antigen-primed CD8 cells can cause graft failure without major effector pathways

Stem Cell Transplantation - Early post-transplant proteinuria may mark glomerular vasculopathy

Stem Cell Transplantation - Fibrin gel could act as delivery system for mesenchymal stem cells

Stem Cell Transplantation - Human hematopoietic cells can contribute to liver recovery

Stem Cell Transplantation - Interleukin-7 may improve post-transplant T-cell recovery

Stroke - Aspirin may be better preventive than ticlopidine in African-American patients

Stroke - Study finds intravenous immunoglobulin may induce stroke in some patients

Surgical Blood Loss - Second generation fibrin glue improves hemostasis after throat surgery

Tissue Bank - LifeNet releases Optium, a demineralized bone matrix

Tissue Regeneration - Faster method for growing adult stem cells for bone regeneration wins award

Transfusion Medicine - Bone marrow can enhance hydroxyapatite-induced bone healing

Transfusion Medicine - Risks associated with transfusions in Canada characterized

Transplant Medicine - Final results of phase IIa kidney transplant trial announced

Transplant Medicine - Relapse of malignancy after bone marrow transplant is treatable with lymphocytes

Transplant Medicine - Study: Thymoglobulin cut rejection rate by nearly 50%

West Nile Virus - Food and Drug Administration says screening tests will be ready to protect blood supply

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