Stem Cell Research

Embryonic cells can differentiate into transplantable hepatocytes

Published in Blood Weekly, July 3rd, 2003

Clinically useful hepatocytes can be derived from embryonic stem cells.

Embyonic cells "provide a unique source for tissue regeneration," scientists in Japan explained.

H. Yamamoto and colleagues working at the National Cancer Center in Tokyo "examined whether mouse ES cells can efficiently differentiate into transplantable hepatocytes."

"ES cells were implanted into mouse livers 24 hours after carbon tetrachloride intoxication," after which "ES-derived cells with several hepatocyte-cell-markers were generated," they reported. These cells "were able to grow in vitro and showed morphology consistent with typical mature hepatocytes...

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Source: Blood Weekly (2003-07-03)

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