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Stem Cell Transplantation

Low dose improves survival in peripheral blood recipients

Published in Blood Weekly, July 10th, 2003

Low stem cell dose improves survival in patients who receive peripheral blood transplants.

"Allogeneic peripheral blood stem cell transplantation (PBSCT) has emerged as an alternative to bone marrow transplantation," researchers in France explained. However, "PBSCT can be associated with a higher incidence of chronic graft-versus-host disease (cGVHD)."

M. Mohty and colleagues at the Paoli-Calmettes Institute in Marseille "investigated whether there was a correlation between the composition of PBSC grafts (CD34+ and CD3+ cells) and hematological recovery, GVHD, relapse, and relapse-free survival (RFS) after myeloablative HILA-identical sibling...

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