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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . July 17th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Leukemia - Stem cell factor mobilization improves stem cell graft efficacy

Stem Cell Transplantation - Estrogen receptor mutations increase complication risks

Multiple Myeloma - HLA-matched peripheral blood stem cell grafts effective

Stem Cell Research - Deciduous teeth source of multipotent cells

Stem Cell Transplantation - Antithymocyte globulin can cause nonovert disseminated intravascular coagulation

Stem Cell Transplantation - Interleukin-1 genotype influences mortality risk

Acute Myeloid Leukemia - ETO domain responsible for oncogenic effects of AML1-ETO

Anemia - More aggressive identification and treatment needed to improve outcomes

Antiphospholipid Syndrome - Risk of thrombosis is high if antibodies persist; anticoagulants can help

Autoimmunity - Fas-transduced mature dendritic cells become killer antigen-presenting cells

Biophysics - Researchers view protein's structural changes in real time

Bleeding Disorders - New programs designed to help patient access to medications

Cardiac Cell Transplantation - MicroPET imaging helps monitor cell survival

Cell Therapy - MicroSyringe allows for direct injection of adult stem cells

Chronic Hepatitis C - Eicosapentaenoic acid ameliorates ribavirin-related anemia

Chronic Myelogenous Leukemia - Donor lymophocyte infusion may resolve DIC after stem cell transplantation

Critical Care Medicine - Anti-inflammatory compound enters Phase I clinical trial

Dermatology - Granulomatous eccrinotropic lymphomatoid papulosis can be misdiagnosed

Graft-versus-Host Disease - Thymoma can be cause in absence of stem cell transplantation

HIV/AIDS Testing - Molecular screening feasible for dried blood, plasma spots

Hematologic Disease - Irradiation of the spleen can be used to treat splenomegaly

Hematology - A high-expressing human factor IX plasmid corrects hemophilia B in mice

Hematology - Interferon causes life-threatening thrombocytopenia in a hepatitis C patient

Hematology - Prothrombotic environments may foster embolisms in multiple myeloma patients

Hematology - The newly identified gene ZFP91 may be linked to acute myelogenous leukemia

Human Tissue Generation - Grant used to optimize stem cell products

Information Technology - Global Med, Misys Healthcare forge marketing alliance on blood donor management

Kidney Disease - Inflammatory myofibroblastic tumors, once removed, do not appear to recur

Kidney Transplant - Immunosuppressive therapy may give higher risk of pregnancy complications

Kidney Transplantation - Study finds significant benefits in child-to-parent transplants

Leukemia - Cholesterol-modulating agents kill acute myeloid leukemia cells

Leukemia - Histone acetylation participates in leukemic cell gene regulation

Leukemia - Infections complicate cases of acute promyelocytic leukemia treated with AIDA regimen

Leukemia - PML/RARa expression is not a determinant of arsenic sensitivity in leukemia

Leukemia - Rare autoimmune hepatitis follows stem cell transplantation from a sibling

Lipid Studies - High-density lipoprotein binding rates in hepatitis C virus genotypes diverge

Lymphoma - Negative pretransplantation scan foretells likelihood of favorable outcome

MALT Lymphoma - Gastric MALT lymphoma may be cured by eradication of Helicobacter pylori

Malaria Pathogenesis - Plasmodial erythrocyte binding ligand uses novel invasion pathway

Multiple Myeloma - Research shows bortezomib benefits a third of patients

Myocardial Infarction - PET & SPECT help monitor success of progenitor cell transplants

Needlestick Injuries - New needle helps protect against blood-borne pathogens

Neutrophil Activities - Ectosomes are unique and may incite inflammation and signal immune cells

Oncogenesis - Erythropoietin deprivation might be a feasible way to check cancer growth

Oncology - Cationic emulsions improve cancer cell uptake of oligonucleotides

Orthopedics - Bone and bone marrow healing incorporates VEGF and VEGF receptor activity

Osteoporosis - Defective mesenchymal stem cell renewal may be cause

Physics - First-of-its-kind nanoscale sensor has many medical, biotech applications

Platelet Counting - EDTA-CTAD stabilizes blood samples for up to 6 hours for flow cytometry use

Platelet Signaling - Collagen receptor glycoprotein VI has three domains with three distinct functions

Renal Regeneration - Renal failure recovery may be due to expression of Wnt-4 in proximal tubules

Retinoblastomas - New hope for children with eye tumors, cancer

Schistosomiasis - Increased age and DHEAS level independently decrease disease severity

Stem Cell Research - Cbfbeta needed for hematopoietic cell maturation

Stem Cell Research - Cord blood B-cell progenitors are multipotent prior to Pax-5 expression

Stem Cell Research - Embryonic neural progenitors can differentiate into neural crest, floor plate cells

Stem Cell Research - Embryonic stem cell-derived mice are expected to highlight gene studies

Stem Cell Research - Embryonic ventricular zone seen in brains of adult mice

Stem Cell Research - Gfi-1 target genes identified

Stem Cell Research - Hematopoietic cell self-renewal characterized

Stem Cell Research - Notch1 needed for embryonic hematopoiesis

Stem Cell Research - Novel fetal mesenchymal stem cells identified

Stem Cell Research - Novel transcription factor gene identified

Stem Cell Research - Pax5 needed for B-cell development

Stem Cell Transplantation - Cyclosporine prevents graft-versus-host disease in recipients of T cell-depleted grafts

Stem Cell Transplantation - Donor cells from new source ignored by the immune system

Stem Cell Transplantation - Donor cytomegalovirus positivity reduces recipient infection risk

Stem Cell Transplantation - Donor lymphocyte transfusions can prevent imminent rejection

Stem Cell Transplantation - High-dose acyclovir may reduce cytomegalovirus infection risk

Stem Cell Transplantation - Impaired T-cell recovery can increase Epstein-Barr virus infection risk

Stem Cell Transplantation - Real-time PCR assay hastens cytomegalovirus detection

Transfusion-Transmitted Virus - Host elements factor into the viremia of TT virus

Type 1 Diabetes Therapy - Hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes

Umbilical Cord Blood - Senescent T-cell subpopulation characterized

West Nile Virus - New test developed to screen donated blood for WNV

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