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Lipid Studies

High-density lipoprotein binding rates in hepatitis C virus genotypes diverge

Published in Blood Weekly, July 17th, 2003

High-density lipoprotein binding rates in hepatitis C virus genotypes diverge.

"The hepatitis C virus (HCV) virion is associated with lipoproteins and immunoglobulins in the sera of patients with chronic hepatitis C; however, an accurate binding rate of HCV to lipoproteins or immunoglobulins has not yet been elucidated. Therefore, the accurate binding rate of HCV to low-density lipoproteins (LDL), high-density lipoproteins (HDL), and immunoglobulins was measured quantitatively by a real-time PCR assay," scientists in Japan reported.

"The immunoglobulin binding rate of HCV was found to be greater than 97.5% in most patients, as compared with an LDL...

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