Stem Cell Transplantation

Antithymocyte globulin can cause nonovert disseminated intravascular coagulation

Published in Blood Weekly, July 17th, 2003

Antithymocyte globulin can increase coagulation in stem cell transplant recipients.

Researchers in California "assessed the effect of rabbit antithymocyte globulin manufactured by Fresenius (ATG-F) on the hemostatic system in patients (n = 12) with various hematological malignancies undergoing hematopoietic stem cell transplantation (HSCT) from HLA-matched unrelated donors."

"For this purpose," M. Weber and coauthors at Scripps Research Institute in La Jolla "monitored different parameters of coagulation before, during and after the administration of ATG-F."

"As a control group, we recruited patients (n = 10) undergoing HSCT from...

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Source: Blood Weekly (2003-07-17)

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