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Blood Testing

Novel method improves detection of fetal cells in maternal blood

Published in Blood Weekly, July 31st, 2003

A novel method improves the detection of fetal cells in maternal blood samples.

"Isolation and analysis of intact fetal cells in maternal blood is an attractive method of non-invasive prenatal diagnosis; however, detection levels are not optimal," researchers in the United States explained. "The poor sensitivity and inconsistent recovery of fetal cells is compounded by small numbers of circulating fetal cells and loss of fetal cells during enrichment procedures. Optimizing selection criteria by utilizing less complicated methods for target cell enrichment is essential."

In their study, F.Z. Bischoff and coauthors at the Baylor College of Medicine...

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