Kidney Transplantation

Epstein Barr viral load can fluctuate without development of PTLD

Published in Blood Weekly, August 7th, 2003

In renal transplant patients, EBV can have a fluctuating serological viral load without development of PTLD.

"Post-transplant lymphoproliferative disorders (PTLD), ranging from lymphoid hyperplasia to clonal malignancy, are a severe complication arising in solid organ transplant patients. Their reported incidence ranges from 1-20%, according to factors such as type of transplanted organ and age of recipient. A strong correlation between Epstein Barr virus (EBV) infection, the grade and type of immunosuppression and the development of PTLD has been recognized," researchers in Italy report.

"The detection and quantification of EBV-DNA load in...

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Source: Blood Weekly (2003-08-07)

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