Stem Cell Research
Pulmonary side population cells characterized
Published in Blood Weekly, August 7th, 2003
SP cells "are a rare subset of cells found in various tissues that are highly enriched for stem cell activity," researchers in the United States explained. These cells "can be isolated by dual-wavelength flow cytometry because of their capacity to efflux Hoechst dye, a process mediated by the ATP-binding cassette transporter breast cancer resistance protein (Bcrp) 1."
"By performing flow cytometry of enzyme-digested mouse lung stained with Hoechst dye," R. Summer and colleagues at Boston University "found that SP cells comprise 0.03% - 0.07% of total lung cells and are evenly...
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Source: Blood Weekly (2003-08-07)
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