Leukemia
Insertion of MLL sequences is a rare abnormality associated with infant leukemia
Published in Blood Weekly, August 14th, 2003
According to recent research published in the journal Genes Chromosomes & Cancer, "MLL gene rearrangements leading to production of MILL fusion proteins are commonly detected in infant leukemia patients.
"The most common MLL fusion associated with infant leukemia is the MLL-AF4 fusion. A single case of chromosomal rearrangement leading to production of an MILL fusion with AF5Q31, a gene structurally similar to AF4, has been detected recently in the malignant cells of an infant leukemia patient," wrote R. Deveney and colleagues, National Cancer Institute, Genetics...
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Source: Blood Weekly (2003-08-14)
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