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Stem Cell Transplantation

Extracorporeal photochemotherapy may be effective for children with graft-versus-host disease

Published in Blood Weekly, August 21st, 2003

Photochemotherapy may be effective against graft-versus-host reactions in pediatric stem cell graft recipients.

In a recent study from Italy, scientists "aimed to ascertain whether extracorporeal photochemotherapy (ECP) is an effective treatment for pediatric patients with refractory graft-versus-host disease (GVHD)."

"From January 1992 to December 2000, 77 children (median age 8.6 years) with either acute (n=33) or chronic (n=44) GVHD, resistant to conventional immunosuppressive therapy, were treated with ECP in four Italian pediatric hospitals," according to C. Messina and coauthors at the University of Padua.

"After ECP, acute...

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