Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . August 28th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Stem Cells - Studies identify key genes involved in blood vessel development
Umbilical Cord Blood - High-level production of cord blood-derived erythroid cells possible
Acute Lymphoblastic Leukemia - Serial MRD monitoring after stem cell transplantation has little value for ALL patients
Cancer Therapy - Stem cell factor may help prevent anemia during chemotherapy
Stem Cell Transplantation - HLA-DR11 expression protects against acute GvHD
Stem Cell Transplantation - Persistently high alemtuzumab levels retard immune recovery after stem cell transplantation
Acute Myeloid Leukemia - Mortality risk factors identified for AML patients undergoing reduced-intensity HSCT
Acute Myeloid Leukemia - Mutation may contribute to AML
Anemia - FDA requests more information on Hemopure for marketing application
Anemia - Treatment for anemia underused for patients with kidney disease or heart failure
Behcet Disease - Patients with active disease have higher thrombomodulin than controls
Bleeding Disorders - Impaired G alpha(i1) expression and signalling may affect platelet aggregation
Blood Testing - AvoSure PT PRO is has advantages over previous portable monitors
Chronic Myeloid Leukemia - Phase I/II clinical study completed for Theralux
Depression - Creation of new neurons critical to antidepressant action in mice
Divestiture - Bankruptcy court approves sale of Eligix system to Miltenyi Biotec
Drug Safety - In vitro toxicity of alkylating agents in myeloid clonogenic assays compared
Embolism - Coagulation proteins stimulate thrombotic events in those with gastric cancer
Finance - Blood-screening product sales help drives company's strong second quarter
Finance - Cell transplantation company announces second quarter results
Finance - Private placement to fund clinical trials, operations, and other general purposes
Follicular Lymphoma - Higher grade transformation associated with diverse genetic lesions in lymphoma
GI Bleeding - Positive phase III results reported for proton pump inhibitor
Graft Versus Host Disease - Tolerized CD4+ T cells can stop GVHD response of naive alloreactive cells
Hematology - Bone marrow angiogenesis may promote plasma cell migration in multiple myeloma
Hematopoiesis - Thymus-dependent NK T cells need rel/NF-kappa B to develop
Hemophilia A - Advate, a clotting therapy, gets FDA approval
Hepatitis B Virus - HBV DNA persists several years after liver transplantation despite prophylaxis
Hepatitis C Virus - A new model predicts severe HCV-related disease after liver transplantation
Hepatotoxicity - Levetiracetam monotherapy controls seizures in a liver transplant patient
Hormone Replacement Therapy - Patch or gel formulations may cause fewer venous blood clots
Hurler Syndrome - Stem cell transplantation can be beneficial for Hurler syndrome patients
Immunomodulation - Therapy with neuropeptides may be a new way to balance the immune system
Legal Issues - AutoloGel maker inks contingency agreement for patent protection
Leukemia - Childhood ALL has long-term survival nearing 80%, new treatments still needed
Leukemia - Complete remission of CLL can be associated with Chinese herbal extract
Liver Disease - Imaging tools determine cost-effectiveness for screening transplant candidates
Lymphoma - FDG-PET has high sensitivity for indolent NHL
Lymphoma Therapy - [F-18]FDG-PET provides valuable information for lymphoma patients undergoing SCT
Mergers and Acquisitions - Dialysis service provider expands its presence in Michigan
Microbiology - Manipulation of archaic bacteria could lead to blood substitute
Mistletoe Immunoactivity - Low-dose mistletoe lectin-1 does not increase TNFalpha and IL-6, high doses do
Myelodysplastic Syndrome - Recombinant erythropoietin effective for MDS patients
Needlestick Injuries - Alliance targets sales of products that reduce exposure to bloodborne pathogens
Non-Hodgkin Lymphoma - Companies announce commercial availability of Bexxar therapeutic regimen
Pancreatitis - Plasma exchange resolved a case of post-transfusion purpura
Platelet Peptide - Glycoprotein VI also found on the surface of vascular endothelial cells
Platelet Transfusion - Thromboelastography parameters MA, K may help assess platelet transfusion needs
Protein Therapy - First company founded on UCF biotechnology formed
Psychiatry - Status before liver transplantation predicts post-transplant mental health
Renal Rupture - Bilateral renal rupture occurs in a patient on hemodialysis
Renal Transplantation - Kidney can be transplanted into an ileocecal reservoir
Research Funding - Grant funds research to develop tissue-engineered solutions for heart disease
Rotary Blood Pumps - Control strategy can maintain physiological perfusion with rotary blood pumps
Schnitzler Syndrome - Thrombophilia can result from antiphospholipid antibodies, elevated homocysteine
Septicemia - Transcriptome data used to unravel fine structure of genes involved in sepsis
Sickle Cell Disease - Beta7-beta132 salt bridge plays key role in hemoglobin stability
Staphylococcal Infection - S. aureus-collagen binding plays key role in infected thrombi development
Stem Cell Research - Hematopoietic cell-released interleukin-15 modulates protein expression
Stem Cell Therapy - Akt-expressing cells restore 80-90% of lost myocardial volume following MI
Stem Cell Transplantation - Non-TCD stem cell transplants from mismatched family donors feasible for children
Stem Cell Transplantation - Novel murine model may aid study of human NK cell development
Stem Cell Transplantation - Optimism linked to improved short-term survival in stem cell transplant recipients
Thrombocytopenia Purpura - Pregnancy with ITP can result in healthy babies, if managed by team of doctors
Transduction - Autonomous PDX-1 transduction may offer a safer way to stimulate insulin
Transfusion Medicine - Soluble complement receptor 1 can treat immune-mediated destruction of red cells
Transplant Medicine - Hopkins doctors perform first triple kidney transplantation operation
Trypanosoma Cruzi - T-cell induced myocarditis may be controlled via targeted inflammation reduction
Vector Development - Listeriolysin O improves the delivery efficiency of antisense nucleotides
Virology - Donor or recipient HCV infections can predominate after liver transplantation
Virus Surveillance - Epitope-blocking ELISA can detect West Nile antibodies in horse, cat, pig sera
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