Immunology
Inactivated parapoxvirus ovis protects against hepatitis and herpes viruses
Published in Blood Weekly, September 4th, 2003
"It is known that some viruses are able to induce vigorous immune reactions. This study shows that inactivated parapoxvirus ovis (Orf virus), strain D1701 (PPVO), induces an autoregulatory cytokine response that involves the upregulation of interleukin (IL)-12, IL-18, interferon (IFN)-gamma and other T helper 1-type cytokines and their subsequent downregulation, which is accompanied by induction of IL-4. An increase in IL-10 expression was also found in the livers of PPVO-treated mice," scientists in the United States report.
"PPVO protects mice from lethal herpes simplex...
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Source: Blood Weekly (2003-09-04)
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