Hematology
Contact-dependent signaling occurs during late events of platelet activation
Published in Blood Weekly, September 11th, 2003
"Signaling events downstream from collagen receptors and G protein-coupled receptors are responsible for the initiation and extension of platelet plug formation. This creates the platelet plug and hopefully results in the cessation of bleeding," investigators in the United States report.
"It is not, however, all that is required for hemostasis, and growing evidence is emerging that the perpetuation of a stable hemostatic plug requires additional intracellular signaling," said Nicolas Prevost and colleagues at the University of Pennsylvania. "At least part of this...
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Source: Blood Weekly (2003-09-11)
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